In situ Hybridization to Evaluate the Wound Healing Process of a Bilayered Living Cell-Based Construct (Apligraf®) in a Nude M

نویسندگان

  • Cecile F. Rousseau
  • Aurelie Pagnon-Minot
  • Sylviane Guerret
  • Daniel J. Hartmann
  • Vincent Ronfard
  • Aurelie Nallet
  • Agatha Zawadzka
چکیده

Galway, Ireland In situ Hybridization to Evaluate the Wound Healing Process of a Bilayered Living CellBased Construct (Apligraf®) in a Nude Mice Model Cecile F. Rousseau, PhD and Aurelie Pagnon-Minot, PhD 2 ; Sylviane Guerret, PhD; Daniel J. Hartmann, PhD ; Vincent Ronfard, PhD Corresponding Author: [email protected] 1 Organogenesis Inc., 150 Dan Road, Canton, MA 02021, USA; 2 University Claude Bernard Lyon 1, Faculty of Pharmacy, Laboratory "Tissue Repair, Biological Interactions and Biomaterials" UPSP 200703-135, 8 ave. Rockefeller, 69008, Lyon, France and 3 Novotec, 13-15 rue J. Monod, 69007, Lyon, France

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Investigating the Antibacterial Property of Silver Nanoparticles in Alginate Wound Dressings

Abstract Introduction: Nanosilver is a nanotechnology product with antimicrobial property. It can improve efficiency, reduce cost and increase antimicrobial durability and performance of wound dressing. Objective: This research intended to introduce a dressing that accelerated and improved the wound healing process by keeping the wound area moist and simultaneously prevented colonization by m...

متن کامل

The importance of both fibroblasts and keratinocytes in a bilayered living cellular construct used in wound healing

Cross talk between fibroblasts and keratinocytes, which maintains skin homeostasis, is disrupted in chronic wounds. For venous leg ulcers and diabetic foot ulcers, a bilayered living cellular construct (BLCC), containing both fibroblasts and keratinocytes that participate in cross talk, is a safe and effective product in healing chronic wounds. To show the importance of both cell types in BLCC,...

متن کامل

دورگه‌سازی در محل؛ اصول و کاربردها : مقاله مروری

In situ hybridization (ISH) is a method that uses labeled complementary single strand DNA or RNA to localize specific DNA or RNA sequences in an intact cell or in a fixed tissue section. The main steps of ISH consist of: probe selection, tissue or sample preparation, pre-hybridization treatment, hybridization and washing, detection and control procedure. Probe selection is one of the important ...

متن کامل

An economic assessment of Apligraf (Graftskin) for the treatment of hard-to-heal venous leg ulcers.

Several recent advances in wound care may offer promise for the treatment of hard-to-heal venous leg ulcers. One such treatment is Apligraf (Graftskin), a bilayered, living human skin construct. To assess the economic impact of Graftskin, a model was constructed to compare the annual medical costs and cost-effectiveness of treating hard-to-heal venous leg ulcers with Graftskin vs. compression t...

متن کامل

A New Mathematical Model to Investigate Drug Treatment on the Overall Process of Wound Healing

The absence of a universally accepted mathematical model for assessment of the effectiveness of drugs in the process of wound healing is one of the problems the health professionals have been faced. In this study, an “empirical” mathematical model is presented to evaluate its reliability from an experimental viewpoint and from a comparative aspect with previous models used to study wound healin...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2010